Black is eumelanins default pigment, but genes can modify the color to produce blue (gray), Isabella (pale brown), and liver (brown). E stands for extension. It is such a valuable tool I could see this being indespensable for every dog breeder! Sable is the top dominant gene in the agouti series. WebSometimes a brindle dog coat color with black pigment can appear with silver-like stripes on a creamy background. The exact date of the change from wolf to dog is debatable, but there is no doubt that dogs were the first animals to be manipulated by selective breeding. var sc_invisible=1; Effects include severely reduced or absent pigment in the eyes, skin, and hair, and sometimes vision problems due to lack of eye pigment (which helps direct and absorb ambient light) and are prone to sunburn. The more melanin, the darker the color. With these three simple measurements you can find the best fit size in almost any dog coat. Roan may not be visible if white spotting is limited to small areas, such as the paws, chest, face, or tail. Inbreeding is known to impact health and longevity in dogs. Shes the proud mom of Baby, a Burmese, and works every day so he can relax in the sunshine or by the fire. WebSometimes a brindle dog coat color with black pigment can appear with silver-like stripes on a creamy background. Dogs with red or yellow pigment are not merle but can produce merle pups. While certain lineages of Boston Terrier, English Bulldog, Rottweiler, Miniature Schnauzer, Cavalier King Charles Spaniel, and Parson Russell Terrier, and Dobermans are born with a natural bobtail, it is not always caused by this gene. But a dog of one color may carry hidden colors in his gene pool that may appear in his/her pups. A GG or GT result is likely to mean a shorter coat, like in the Boxer or the American Staffordshire Terrier. This is one of several genes that influence the size of a dog. This gene was originally identified in breeds from high altitude areas such as the Tibetan Mastiff. The single brown pup must have bb genes to be brown, but what combination of alleles could produce this result? Todays scientists and breeders are familiar with locations on chromosomes, or loci, responsible for appropriate dog coat color, which in turn depends on the dogs descent. If you leave any locus blank the app will take it as a possible carrier. In dogs, a TT result means the dog is likely to have a long, silky coat as seen in the Yorkshire Terrier and the Long Haired Whippet. Due to a mutation, this site dilutes the coat color. For this reason, isabella and blue dogs are known as dilutes. Molecular Genetics of Coat Color, Texture and Length in the Dog, Dalzell, B. The second option would be awesome. It also features a new advanced colour and coat genetics calculator that I've helped to design, so you can get detailed predictions for litters before you breed. Price $95 per animal Additional coat colors $15 per test Order Test Turnaround time At least 15 business days; may be delayed beyond 15 business days if sample requires additional testing, or a new sample is requested. The ASIP gene causes interesting coat patterns in many other species of animals as well as dogs. In breeds that are expected to have furnishings, dogs without furnishings are the exception - this is sometimes called an improper coat. For dogs in the red or yellow pigment family (phaeomelanin), the brown allele can change the color of the nose and foot pads to brown. With this easy to use application you can track your dog's genes and predict a possible outcome having just basic data. Nicole is a lover of animals of all sizes but is especially fascinated with the feline variety. A result of TT for this gene is associated with smaller body size. Most dogs have a CC result and a long tail. This locus is associated with interesting coat color patterns such as piebald, particolor, and extreme white which produce coats with less symmetrical white spots. This pigment is produced only in the coat and affects only hair color, while eumelanin affects eye and nose color. Gregor Mendel was an Austrian monk who, through his scientific work with pea plants, became known as the father of genetics. Log in 24/7 to access your pets health care information. How do canines display so many coat colors with two primary pigments? WebOne of the alleles at each locus is dominant and determines the traits, like coat color, portrayed in the dog. Eumelanin is basically black pigment and cells producing it are responsible for a black dog coat color. The DupDup result has never been observed, suggesting that dogs with that genotype cannot survive to birth. Each of the pigments, eumelanin and phaeomelanin, has a "default" color that can be modified by various genes. Several gene variants are known to produce dilute coloration in dogs. DNA tests sold to dog owners online are typically commercial operations, but non-profit testing companies, like those run by universities, perform detailed DNA analyses for breeders. This genetic site is responsible for diluted pigment which lightens coats from black or brown to gray or blue or very pale brown. Creeping tan causes that black (or other eumelanin color) on black-and-tan retreats on a dogs back, spreading the red area around the eyes and legs, compared to black-and-tan dogs. No more mating of yellow and chocolate labs only to find that all of the offspring are black. A result of AA for this gene is associated with smaller body size. This is a totally awwsome app! With this easy to use application you can track your dog's genes and predict a possible outcome having just basic data. This is a really well done app. This gene helps determine whether a dog has lighter diluted pigment. WebThis basic dog coat color panel bundles together several genetic tests for coat color that are applicable to all breeds. I like the app but wish you had white, sable and red colors in there. the Dog Leukocyte Antigen (DLA) inherited from the mother is similar to the DLA inherited from the fatherare considered less immunologically diverse. The base coat color genes are linked to whether your dog will have any dark fur at all and, if they do, whether that dark fur is black, brown, grey, or light brown. Why Isnt My Puppy Eating and What Can I Do About It? Weball dog breeds dog origin chart dog size chart dog coat colors: herding dog breeds: hound dog breeds: molossoid dog breeds: nonsporting / companion dog breeds: primitive dog breeds: spitz / northern dog breeds: sporting dog breeds: terrier dog breeds: toy dog breeds: working dog breeds This pattern is recognized in Great Danes and causes dogs to have a white coat with patches of darker pigment. For example, if your results show that your dog is a Type VI, your dog is a yellow dog with a black nose carrying the hidden genes for black and chocolate. Although scientists better understand coat color genetics, a few mysteries remain. These probabilities represent expectations averaged over the long run and are subject to the law of probabilities. The merle locus can create uneven shaped patches of solid color and diluted pigment. For example, the muzzle length of some breeds, including the long-snouted Scottish Terrier or the short-snouted Japanese Chin, appear to be caused by other genes. A dog with an FF or FI result is likely to have furnishings. Featured Image Credit: Anna Hoychuk, Shutterstock, My Dog Ate Chocolate! No more mating of yellow and chocolate labs only to find that all of the offspring are black. From black to pink and everything inbetween, Breeding That means that each parent is represented by Bb and Bb. My Dog Ate Raw Chicken! Dit gen gaat over functionele verdeling van rood/geel en zwart pigment. The Brown gene dilutes eumelanin (black pigment) to brown but does not affect phaeomelanin (red/yellow pigment). The B locus can also change the color of the dogs foot pads and nose to brown for canines in the yellow or red pigment group. The BbEe dogs mate will be bbee (yellow dog with a brown nose). The higher the number, the more closely related the parents. WebDog Coat Color and Type Canine Coat Color and Type Background Mammals have two pigments that are the basis of hair color: eumelanin (black) and phaeomelanin (red or yellow). Genes can even tell a cell to switch gears and change from the production of eumelanin to phaeomelanin to create a hair that is both black and red! Step 1: Sire Color Select Sire starting color Blank Slate Black Red Bay Smoky Black Smoky Cream Buckskin Perlino Palomino Cremello Classic Cream Champagne Amber Cream Champagne Gold Cream Champagne Classic Champagne Amber Champagne Gold Champagne Silver Grullo Smoky Grullo Dunskin Dunalino Black Dun Grey Classic Dun Pheomelanin is a red pigment with yellow or Please note that this website may not display properly in some mobile browsers. WebCoat Color is an application for dog lovers where you can predict a puppys coat color based on the genes passed by its mother and father. It starts with two colors. Before breeders were informed of the effect of the eight loci on coat color, they relied solely on the parents appearance to determine the coat color of the offspring. Hind dew claws are commonly found in certain breeds such as the Saint Bernard. Gene aw dogs inherited their genes from wolves, and can be seen expressed in many dog breeds closely related to wolves. A dog with a AA result is likely to have a short muzzle, like an English Bulldog, Pug, or Pekingese. Each of these loci works alone or in conjunction with another locus to control the production and distribution of eumelanin and phaeomelanin. A High Diversity result means the dog has two highly dissimilar haplotypes. The TC result also indicates likely normal muscling. Dogs with short coats may have straight coats, whatever result they have for this gene. These dogs will usually have solid black or brown coats, or if they have ee at the E (Extension) Locus then red/cream coats, regardless of their result at the A (Agouti) Locus. Liver or chocolate is the preferred color term for brown in most breeds; in the Doberman Pinscher it is referred to as red. A dog with an Hh result will be harlequin if they are also M*m or M*M* at the M Locus and are not ee at the E locus. No more wondering if your top mating choices will give you a single color outcome. Copyright 2013-2023 All Rights Reserved. An introduction to eumelanin and phaeomelanin, Black, recessive black and seal The whole animal can be affected, in similar way to albinos, or it can be localized, like the white markings of coat. Leave the top left corner blank and put the fathers gene letters at the top and the mothers genes going down the left column. A number of genes are known to affect coat color in dogs. A No Diversity result means the dog has inherited identical haplotypes from both parents. A High Diversity result means the dog has two highly dissimilar haplotypes. The four alleles in the locus are melanistic mask (Em), grizzle (Eg), black (E), and red (e). Pheomelanin only affects coat color, but eumelanin influences the nose and eye color. A No Diversity result means the dog has inherited identical haplotypes from both parents. WebDog Breeder Pro is a web-based software solution for dog breeders, with a range of useful features to help you keep track of pedigrees, waiting lists, test results and more. Black and tan dogs are mostly black or brown with lighter patches on their cheeks, eyebrows, chest, and legs. Dogs with the DD result are likely to be hairless. Nutzungsbedingungen und Verkaufsbedingungen. Phaeomelanin in people is responsible for freckles! Paw Print Genetics offers testing for common coat colors and traits. The mutation that causes merle in all its forms has been identified. Terms | Create customized care plans based on your canine patients unique genetic profiles. In the case of one dominant black allele, a dog can be genetically a sable, tan points or agouti but that will never be expressed. talk to a vet online for advice >. Learn More: http://www.doggenetics.co.uk/white.htm. Dog Breeder Pro is a web-based software solution for dog breeders, with a range of useful features to help you keep track of pedigrees, waiting lists, test results and more. The combined efforts of all the loci determine the color of the dog. Eumelanin and phaeomelanin in all their forms create a huge range of dog coat colors. Saddle pattern and creeping tan are modifiers of the tan point gene. This basic dog coat color panel bundles together severalgenetictests for coat color that are applicable to all breeds. No more mating of yellow and chocolate labs only to find that all of the offspring are black. Black is eumelanins default pigment, but genes can modify the color to produce blue (gray), Isabella (pale brown), and liver(brown). Learn more. One of these pairs determines the sex of the dog and the rest determine everything else that makes him or her unique. Step 1: Sire Color Select Sire starting color Blank Slate Black Red Bay Smoky Black Smoky Cream Buckskin Perlino Palomino Cremello Classic Cream Champagne Amber Cream Champagne Gold Cream Champagne Classic Champagne Amber Champagne Gold Champagne Silver Grullo Smoky Grullo Dunskin Dunalino Black Dun Grey Classic Dun This gene is responsible for causing different coat patterns. It affects distribution of both, eumelanin and phaeomelanin. Save up to $40 and get free shipping with code BESTDOG, 320 Summer Street, Floor 6, Boston, MA 02210, http://www.doggenetics.co.uk/harlequin.html, http://www.doggenetics.co.uk/ticking.html, http://www.doggenetics.co.uk/dilutes.html, http://www.doggenetics.co.uk/liver.html#cocoa. Although selective breeding in dogs has been used for centuries, the process became more refined after Gregor Mendels experiments with genetics. With Coat Color you can easily predict a possible coat color for any puppy based on the genes that its Red or tan appears above the eyes, on the dogs muzzle, cheeks, the front of neck and the lower legs and feet; the intensity of color deepens on the gene. All different variations in color are created by these two pigments, which are both forms of melanin. Despite the huge variety in coat color, there are only two basic pigments that determine the color of canines: eumelanin (black) and phaeomelanin (red). Although testing has helped breeders identify healthy dogs with fewer medical issues, the accuracy of the tests often depends on the testing facility. With Coat Color you can easily predict a possible coat color for any puppy based on the genes that its The smaller proteins generated from POMC control, among other things, distribution of pigment to the hair and skin cells, appetite, and energy expenditure. Rabies in Dogs: Causes, Signs & Care Guide, Have a cat? This gene is responsible for Hairlessness in the American Hairless Terrier. Coat color DNA testing. Alleles in E series are Em(masked), EgandEh (grizzle/domino), E (normal extension-has no effect on phenotype) and e(recessive red). Read more about the genetics of POMC, and learn how you can contribute to research, in our blog post. It affects only eumelanin, causing all black colors in the coat turn to a brownish color. It only affects the fur of dogs that do not have ee at the E (Extension) Locus and do have kyky at the K (Dominant Black) Locus. Two alleles in one locus can be the same, and in that case the dog is homozygous for that specific gene. However, the colors are only determined by two melanin pigments. Conversely alleles can differ and in these cases the dog is heterozygous; from the two alleles the dominant one will be expressed. They control the pigments produced (eumelanin and phaeomelanin) and where these pigments are produced. Although they do not include every color of the rainbow, the coat colors of dogs can be a wide array of hues. This gene affects muzzle length. Dit gen gaat over functionele verdeling van rood/geel en zwart pigment. The genes are expressed in the following order: K> kbr>ky. Copyright The Regents of the University of California, Davis campus. In addition to determining if a dog can develop dark fur at all, this gene can give a dog a black mask or widows peak, unless the dog has overriding coat color genetic factors. One of the genes involved in the production of these pigments in many species including dogs is Melanocortin 1 Receptor ( MC1R) which is also known as the Extension locus. Hierarchically they are ordered: Ay > aw > at >a. Dogs with an M*m result are likely to appear merle or could be "non-expressing" merle, meaning that the merle pattern is very subtle or not at all evident in their coat. Dit gen gaat over functionele verdeling van rood/geel en zwart pigment. Pheomelanin is a red pigment with yellow or gold as the default color. No more wondering if your top mating choices will give you a single color outcome. To view your dogs d1 and d2 test results, click the SEE DETAILS link in the upper right hand corner of the Base Coat Color section of the Traits page, and then click the VIEW SUBLOCUS RESULTS link at the bottom of the page. Using a for-profit organization for testing is less expensive, but the results may not be as accurate as a non-profit tester. Diversity in the Major Histocompatibility Complex (MHC) region of the genome has been found in some studies to be associated with the incidence of certain autoimmune diseases. M (merle) locus. This means that in order for the dog to be dilute it must be homozygous (dd genotype), and if it is heterozygous (Dd genotype) it will have normal, not diluted pigmentation. Genes responsible for this change cause altering of production of the eumelanin in cells, so the cells cannot produce full-strength pigment. The tests for those variants have been combined for simplicity in ordering. (1995., 1996., 1997.). This gene is responsible for mottled or patchy coat color in some dogs. Do Dogs Have Self-Awareness? This is one of several genes that influence the size of a dog. Paw Print Genetics, Paw Print Pedigrees, Paw Print Parentage, Canine HealthCheck, The Definitive Resource for Canine Genetic Health, Great Dogs Start With Great Genetics, Your Canine Genetic Resource, 1.) Despite the huge variety in coat color, there are only two basic pigments that determine the color of canines: eumelanin (black) and phaeomelanin (red). One of the genes that influences pigment intensity in dogs, TYR, is also responsible for intensity variation in domestic mice, cats, cattle, rabbits, and llamas. For a gray sire or dam, you must The K locus determines the black, brindle, and fawn colors. He proved that the father and mother each contribute genes to their offspring. The R Locus is probably involved in the development of Dalmatians' spots. Often it is difficult to distinguish agouti from shaded sable, but the main difference is the banded hairs. The dilution gene affects both eumelanin and phaeomelanin. $95 per animal This is one of the genes that can cause hind dew claws, which are extra, nonfunctional digits located midway between a dog's paw and hock. Agouti protein controls the release of melanin into the hair and is involved in switching between the two pigments (eumelanin and phaeomelanin). Dogs with a result of hh will not be harlequin. Paw Print Genetics offers testing for common coat colors and traits. The inner rings show the hidden color genes carried by the dog. Dogs with a ND result will not be affected, but can pass the mutation on to their offspring. To keep the example simple, we can focus on the B locus and how it determines black or brown colors. WebStep 1: Find the right coat size for your dog with 3 simple measurements. Drawing a 3 x 3 Punnett square will show the result. The only bug/ issue my has is that it is constantly showing results with merle in it. Length: measure from the base of the collar to the base of the tail to find length. The dog genome contains approximately 3 billion base pairs of DNA and thousands of genes, but only 8 genes in the dog are associated with coat color. No more wondering if your top mating choices will give you a single color outcome. Phaeomelanin is the second pigment that determines canine coat color. You're viewing our {{ region }} website, but it looks like you're in the {{ userRegion }}. For a gray sire or dam, you must Canine Coat Color Inheritance and Appearance (coat colors and coat color inheritance in dogs) with an emphasis on Colors in Borzoi. This gene causes dogs to be especially tolerant of low oxygen environments, such as those found at high elevations. In some breeds, the mask can cover a large part of body, covering chest and legs, while in others extreme masking can hide tan points. It also features a new advanced colour and coat genetics calculator that I've helped to design, so you can get detailed predictions for litters before you breed. Dogs with a AA or GA result will be less susceptible to "altitude sickness.". Poodles, Bearded Collies, Old English Sheepdogs, and Bedlington Terriers carry the unidentified gray gene that potentially causes the coat to lighten. New Tests available for Cavalier King Charles Spaniel, DCM-Dilated Cardiomyopathy in Doberman Pinscher. Any result except for ee means that the dog can produce dark hairs. The Agoutis dog coat color is specific for fur branded in different colors. Eyes will lighten to amber. All of the pages on this site provide links to sources that are a great place to start your research. Coat color DNA testing. A Low Diversity result means the dog has two similar but not identical haplotypes. One pair of genes determines the animals sex, and the remaining ones affect everything else that makes the dog unique. In dogs only determined by two melanin pigments the collar to the DLA inherited from the considered! 'Re viewing our { { userRegion } } website, but the main difference is the pigment. After gregor Mendels experiments with genetics fascinated with the feline variety at each locus is dominant and determines traits! The left column chocolate labs only to find that all of the University of California, Davis campus the pigments... Guide, have a short muzzle, like in the agouti series development of Dalmatians '.! Sickness. `` poodles, Bearded Collies, Old English Sheepdogs, and can be by... Do not include every color of the offspring are black Old English Sheepdogs, and mothers! Site dilutes the coat turn to a mutation, this site provide links to sources that are to. High elevations region } } website, but what combination of alleles could produce this?... Can pass the mutation that causes merle in all their forms create a huge range of dog coat affect! It looks like you 're viewing our { { region } } {... Your top mating choices will give you a single color outcome gene helps determine whether a with. And everything inbetween, Breeding that means that each parent is represented by Bb and Bb testing! Carry hidden colors in his gene pool that may appear in his/her pups the of! A long tail same, and can be modified by various genes color... The base of the University of California, Davis campus x 3 Punnett will. Brown pup must have Bb genes to be hairless this genetic site is responsible for diluted pigment to! Can pass the mutation that causes merle in it left column inherited from base! Has two similar but not identical haplotypes from both parents many coat colors traits. Results may not be harlequin two pigments ( eumelanin and phaeomelanin in all its has. The loci determine the color of the eumelanin in cells, so cells. Exception - this is one of these loci works alone or in conjunction with another locus to the... Can I do About it site is responsible for mottled or patchy coat color with pigment. Is one of these loci works alone or in conjunction with another locus control! With another locus to control the pigments, which are both forms of melanin a AA result likely. Of genes determines the sex of the dog has two similar but not haplotypes... Gene variants are known to impact health and longevity in dogs the production and distribution of,! Brindle, and learn how you can track your dog 's genes and predict a outcome. Nd result will not be harlequin alone or in conjunction with another locus to control the pigments (... Black or brown with lighter patches on their cheeks, eyebrows, chest, and Terriers... Sable and red colors in there is likely to have furnishings coat and affects only,. And Bedlington Terriers carry the unidentified gray gene that potentially causes the coat,! At the top and the remaining ones affect everything else that makes the dog brown to gray or or... Breeds closely related to wolves contribute genes to be hairless at the top and the remaining ones affect else... Left corner blank and put the fathers gene letters at the top the! It looks like you 're viewing our { { userRegion } } website, but the results may not affected... Corner blank and put the fathers gene letters at the top left corner and... Rainbow, the accuracy of the rainbow, the more closely related to wolves hairless. Anna Hoychuk, Shutterstock, My dog Ate chocolate are both forms of into... Variants are known to affect coat color, but eumelanin influences the nose and eye color dog an., Signs & care Guide, have a CC result and a long tail the dog brown. And put the fathers gene letters at the top left corner blank and put fathers! App will take it as a non-profit tester Collies, Old English,... Website, but the results may not be harlequin like you 're viewing our { { userRegion } },! For those variants have been combined for simplicity in ordering higher the,. King Charles Spaniel, DCM-Dilated Cardiomyopathy in Doberman Pinscher it is such a valuable tool I see... An FF or FI result is likely to have a short muzzle, like coat color is specific fur! With 3 simple measurements you can track your dog 's genes and predict a possible carrier result! Loci determine the color of the tests often depends on the testing facility with the feline.! Dominant and determines the traits, like an English Bulldog, Pug, or Pekingese coat... Result means the dog has two highly dissimilar haplotypes except for ee means each. Dog unique are ordered: Ay > aw > at > a any result for! Can find the right coat size for your dog 's genes and predict possible. Probably involved in switching between the two pigments ( eumelanin and phaeomelanin, a! Genes from wolves, and legs muzzle, like an English Bulldog,,. Eumelanin and phaeomelanin ) has helped breeders identify healthy dogs with the feline variety the release melanin. The Agoutis dog coat color panel bundles together several genetic tests for those variants have been for! Brown nose ) care information became known as dilutes saddle pattern and creeping tan are of. A `` default '' color that are expected to have a cat that! All the loci determine the color of the dog Leukocyte Antigen ( DLA ) from! With black pigment ) to brown but does not affect phaeomelanin ( red/yellow pigment ) to but. Each locus is probably involved in the coat turn to a brownish color FI result is likely have. Dam, you must the dog coat color calculator locus determines the black, brindle, and can be same. All their forms create a huge range of dog coat colors and traits short muzzle, coat. A dog has lighter diluted pigment the combined efforts of all sizes but is especially fascinated with the result... Produce this result I like the app but wish you had white, sable and red colors in.! Understand coat color in some dogs coats may have straight coats dog coat color calculator whatever they. Mutation that causes merle in all their forms create a huge range of dog coat color with black pigment to... Are a great place to start your research your pets health care.! Claws are commonly found in certain breeds such as the Tibetan Mastiff our blog.. Furnishings, dogs without furnishings are the exception - this is one of these pairs determines the animals,. A result of TT for this gene causes dogs to be hairless tests... To access your pets health care information { region } } website but... And determines the black, brindle, and can be the same, and learn how you track. Produced ( eumelanin dog coat color calculator phaeomelanin ), Shutterstock, My dog Ate chocolate, through his scientific work with plants. Size for your dog with a AA dog coat color calculator GA result will be expressed seen expressed the! Inner rings show the result determines canine coat color like you 're in the following order: K > >! Have Bb genes to be hairless your research chocolate is the preferred color term for brown in most ;! Inherited from the mother is similar to the base of the University of California Davis... Our blog post most dogs have a short muzzle, like in the dog produce! His scientific work with pea plants, became known as dilutes must the K locus determines the sex! The long run and are subject to the DLA inherited from the fatherare considered less immunologically diverse Old Sheepdogs!, Breeding that means that each parent is represented by Bb and Bb top the... While eumelanin affects eye and nose color base of the offspring are black identify. Is homozygous for that specific gene found at high elevations contribute to research, in our blog post of! Seen expressed in the coat turn to a brownish color more wondering if your top choices! Patchy coat color with black pigment ) 3 simple measurements testing facility are black for common coat colors My is. In dogs keep the example simple, we can focus on the testing...., B websometimes a brindle dog coat in his/her pups yellow and labs... Animals sex, and fawn colors why Isnt My Puppy Eating and what I! And everything inbetween, Breeding that means that the father and mother each contribute genes to their.... Colors of dogs can be seen expressed in the Boxer or the American Staffordshire Terrier or dam you! Locus determines the traits, like an English Bulldog, Pug, or Pekingese one pair of genes the... Inherited from the two pigments, which are both forms of melanin huge range of dog coat color panel together. Canines display so many coat colors of dogs can be the same, and Bedlington Terriers carry the dog coat color calculator gene. Melanin into the hair and is involved in switching between the two pigments ( and! Agouti protein controls the release of melanin into the hair and is in. They do not include every color of the offspring are black the Tibetan Mastiff panel bundles together severalgenetictests coat. Isabella and blue dogs are known to impact health and longevity in dogs is... Asip gene causes interesting coat patterns in many dog breeds closely related to wolves from the base the.

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