I personally prefer something gentler as many Collies can have sensitive skin, but it really depends on the dog. The vet is really no help. enough to have 4 dogs like I do! Basically, while the FDA has not pulled these drugs from the market, it has asked the product manufacturers to add precautions to their labels while it continues to monitor information submitted by veterinarians, the companies themselves, and individual product users. These three are listed as a new group of drugs called Isoxazolines, and are neurotoxins. He had been taking the it for about 2-3 months. THANK YOU, THANK YOU, THANK YOU! I once used a Hartz product on my male Collie, and he had a pretty bad reaction to it. I dont have much personal experience with this other than giving my MDR1 mutant/normal Collie girl veterinary-prescribed Carprofen when she hurt her paw. Simparica is not a heartworm preventive whereas Simprica TRIO works as a heartworm control treatment. Unless your dogs are exposed to untreated stray or wild animals who are carrying fleas through the winter months, there is no need to give parasite protection to your pets year round. Personally I use Frontline Plus and supplement weekly with a Natural Chemistry spray as a repellent, but I understand that might not be ideal for everyone depending on their situations. Additionally, it can also be given to cats and even pregnant or nursing animals. I grew up in Michigan, and we always discontinued pest products during the cold season. If you click on combination medications in the table of contents at the beginning of the article and read the section on Advantage Multi, youll find that Ive given it a caution rating along with reasons for that rating. But it doesnt hurt mammals. (One such knockoff, Pet Armor Plus, is even available at Walmart.). I have 7 collies and I am reluctant to put them on anything thats not natural , we did get a kitten and found a flea so looking for something to treat all as a precautionary for a month as we are in winter season in Northern Ontario Canada. A couple people claimed that the trick to getting them to work well is to use a slicker brush to part the fur of the mane, to ensure the collar is close to the skin for best effect. Mary. Simparica comes as flavored, chewable tablets and is available in a variety of sizes: 5, 10, 20, 40, 80, and 120 mg. 6. Options: 3 flavors. I love that it quickly kills adult fleas andfour kinds of ticks: American dog tick, brown dog tick, lone star tick, and black-legged tick. Last year I used Frontline Plus with no issues. However, it did make my Collies too itchy. After logging in you can close it and return to this page. (There are 13 other at-risk breeds including Border Collies, Australian Shepherds, German Shepherds, Shetland Sheepdogs, and Old English Sheepdogs, plus herding breed mixes. The manufracturers website lists many different kinds of ticks, and people on this thread talk about using FrontLine for ticks. Vectra is a rather strong product that I wont personally recommend, as so many dogs in the Collie family have sensitivities. 5,10 That's two tasty chews to double your dog's dosing delight each month. Our cat does not socialize with the Collies. Just as another concern, I had two cats die from Advantage Multi. Thats why I use it in combination with an essential oil spray like Natural Chemistry. First, I want to thank you for the time and effort that went into writing this article. Please tell me which is the safest! Is the Frontline the one listed in the article ok in a multi dog family where there is a risk of one licking it off the other? If your dogs arent reacting to it, why are you switching? This is so thorough and helpful! ? With complaints rolling in, the company made adjustments to the Ivermectin content in their product, and Heartgard is now advertised to be safe at the recommended dosage. But according to Dr. Judy Morgan, Neurologic side effects are a possibility with Heartgard., Also, some veteran Collie breeders and owners have horror stories of even MDR1-clear Collies having adverse reactions to medications containing Ivermectin. While I dont believe it be quite as effective as the label says it is though that might have something to do with living in pest-ridden Florida I do find it to be very helpful. ), In regards to your other question, heres what I found for you: Prinovox is the generic alternative to Advocate (in the UK and Australia) and Advantage Multi (in the US) both made by Bayer, just marketed by different names in different countries. (Just bear in mind that Preventic contains amitraz, which is toxic to cats.). I have to tell you that I am no expert, but I would feel the same and be wary of giving Interceptor Plus again. Documented negative reactions were only provoked at higher-than-normal dosages and were comparatively mild, consisting of salivation, ataxia (dilated pupils), and depression. What an awesome article. However, the safety of Interceptor Plus has not been evaluated for pregnant or lactating dogs, and it is not recommended for cats. (Many products dont repel insects, and if they do are often very strong chemical formulations.). She is just 1 year old. I went back and edited my comment for consistency. It is such a relief to know that even if she tests positive there are options that are safe. Hope this helps! My 14 year old Border Collie has had trouble with parasitic medicines since she was a puppy. (I have to give them baths with a very mild or medicated shampoo.) If you choose to use Advantage Multi, great care should be taken to only apply the liquid between your dogs neck and shoulder blades, where it cannot be reached by licking. If the topical treatment (the shampoo) contains some form of -mectin, that could cause a sort of overdose if given in conjunction with Heartgard, which contains Ivermectin. If Ive got time I even put on disposable gloves and rub it into the fur a little better! But I do think K9 Advantix is a good choice for Collies who arent overly sensitive. Best of luck with your new girl! We can eat it. If youre someone who lives in a tick-prone area or likes to take your dogs on woodland rambles (like me), this is a letdown. Simparica Trio is a powerful oral treatment that provides triple protection. However, it will not affect heartworms at all, since they do not infest the gastrointestinal tract. Heartgard has been out long enough that there are cheaper knockoffs available. In a laboratory study, the product was . If you think about it, come back here and let me and other readers know what worked best for you! I have called two divisions of the manufacurer trying to find out whether the products cover all the ticks they list on their website, or only the one tick of concern that they list on their packaging. The flea pills and chews all contain a pesticide called isoxazoline, the FDA said . My plan is to adopt a senior Border to go with my lazy Roughs. Were bringing home an MDR1 heterozygous smooth boy this weekend so Ill definitely be saving the link to this page. Please log in again. No toxicity was seen when affected dogs were given 28 to 35.5 mcg/kg monthly for one year. Thank you again for all your help : ). Hartz products generally dont seem to get very favorable reviews either. I follow this advice, since Im a safe-is-better-than-sorry person. The majority of canines will be fine, but there are enough who will react. She has shown personality signs of that condition ever since, which are controlled by a dose of a quarter pill of trazadone as needed. Observaciones clnicas de salud, Parmetros toma de muestras sanguneas para medidos farmacocintica. After 24 hours, it is considered waterproof and a bath, while alleviating some effects, will not offer as much relief. Fleas were treated with effifax, active ingredient fipronil. Are you also on Instagram, by chance? If the veterinary staff cant see they are prescribing the wrong combination of medications, maybe you can point it out to them.. I also have a 5 month Aussie who the current vet has on Bravecto 1-month and TriHeart. Components Species Test Results Silica colloidal, Ph. THREE OF THE 8 FEMALES WENT INTO ESTRUS. I would probably try something like Advantix II or Frontline Gold before Vectra. One observation: You mention that Credelio has fewer reported seizures (6 in as many months) than other drugs in the isoxazaline class. It was very frightening. Until progress is achieved in ongoing studies, adjustments are made to the medications themselves, and the FDA warning is lifted, Ill have to leave Bravecto in the caution category. I have an 8 year old BC and a 12 week old English Shepherd/Rough Collie mix. (Also, bear in mind that the Permethrin in Zodiac Spot On will make it very dangerous, even toxic, to cats, in case you have any.) Should I give them Trifexis or Sentinel Spectrum? I have been raising and showing collies for 40+ years but am always open to learning. I think Frontline Gold is very effective, and as far as I know there are no MDR1 concerns with it. When sprinkled on a bug that has an exoskeleton (such as bed bugs, ants or fleas) it compromises their waxy coating so that their innards turn into teeny tiny bug jerky. It comes in pill form, starts working within 30 minutes, and will kill all the fleas on a dog within 4 hours. Wash hands after handling the product. One person commented that their Collie had irritation at the point of contact, so they recommended checking frequently to make sure the collar is not irritating the skin. It makes me nervous since I have seen/read plenty of negative things about bravecto and Im also worried to combine bravecto with interceptor. (MDR1 -/-) following single oral administration at 5 times the recommended dose. Honestly, I think K9 Advantix would beat Credelio as far as effectiveness, due to its repellent properties and ability to kill on contact. Dogs with the mutation lack a protein (P-glycoprotein) which is responsible for pumping the drugs from the brain. In the past she was prescribed Bravecto and experienced what I could only assume to be neurological side effects/symptoms such as sporadic limping, weakness and sensitivity to human contact. It is the first drug that combined three active ingredients - sarolaner, moxidectin, and pyrantel. It targets not only heartworms, but also hookworms, roundworms, and whipworms. I just dont know what to do about heartworm treatment and wonder if Interceptor instead of Interceptor Plus would be a better option or more of the same. Trifexis is perhaps the most well-known (and frequently peddled at veterinary clinics) of this combo category. She immediately throws up the medicine, and the Soresto collar left her skin raw underneath (I didnt notice until I took it off to bathe her). Happy to help! Great summary! Though I already mentioned Nexgard as being included in the FDA statement, Im dealing with it separately because it is such a well-known product. Id like to have a Smooth Collie in the future. Simparica Trio Chewable Tablets for Dogs works to prevent heartworms as well as treat lone star ticks, black-legged ticks, Gulf Coast ticks, American dog ticks, brown dog ticks, fleas, roundworms, and adult hookworms. However, it does claim to kill fleas on contact. The key to getting this spray to work well is to apply it well (rub against the lay of the coat while spraying the roots of the hair to get down to the skin); thoroughly (to the underbelly, legs, and paws); and often (at least once a week, more if your dog gets wet). 1,9 And the fact is, dogs love both chews. 1 x 40mg tablet for 22.1 to 44 pounds. This gave me a great start for research. It just depends on the individual dog. . When reading about Seresto, their website said it doesnt work well on dogs with heavy coats, ie. I am so excited. Opioid pain relievers are essential drugs, and appear safe if used with care. (CAS 112945-52-5) Oral Acute LD50 Rat > 22500 mg/kg Skin corrosion/irritation Prolonged skin contact may cause temporary irritation. This product contains moxidectin (a macrocyclic lactone), therefore special care should be taken with Collies, Old English Sheepdogs and related breeds or crossbreeds, to correctly administer the product as described under dosage schedule. It covers fleas, ticks, and heart worms. Id like to have a Border Collie one day, but as I have some health issues Im not sure I could keep up with one. For the majority of dogs, Advecta is probably fine! Tap to zoom. Thank you for all your research and article!! I have a toy Aussie(Lola), and we are taking her to Mexico this winter and she needs to have certain treatments required by customs to bring her across the border, my vet advised me that Heartguard and Bravecto or Nexguard are safe for her at the correct doses. As far as I know, Huskies have not been identified as prone to having the MDR1 gene mutation, as it is mainly a problem found in herding breeds. Unlike Nexgard, Bravecto, and Simparica, Credelio had very few (6 reported seizures in as many months) negative reports submitted to the FDA; but it was still mentioned in the FDA report as required to add a precaution to its label because a) its main ingredient is in the -laner family, and b) it is such a new product. Dr. Morgan concluded her story with: Be your pets advocate. Unacceptable for me) He is MDR1 clear. Or, a dog may walk on a lawn treated with pesticides, and absorb it through or lick it off their paw pads. . Description: Simparica TRIO is a monthly chewable tablet that protects your dog against heartworm disease, five types of ticks, fleas, roundworms and hookworms. The parasite protections that target multiple parasites with just one topical application or administration of a pill are extremely appealing due to their convenience. Product Description. For those of you who want proof or a more in-depth explanation of whyIve given each medicine its label, feel free to read the commentary under each product and even follow the embedded links for further reading. The vet thought he would be nice and put Advantage Multi on our cats. Id like to thank you so very much for this in depth article. Simparica Trio can be described as a broad-spectrum parasite preventative that offers protection and treatment to dogs. Your article was appreciated and helpful! 1x 10mg tablet for 5.6 to 11 pounds. It is approved for use on puppies at least 3 pounds in weight and 7 weeks of age, cats, and even ferrets. At this point, Credelio is really the only long-term oral flea/tick protection I would personally use, especially since Ive given it to Gustav, my male Collie who is also a carrier for MDR1, and Freckles, my female Aussie mix, and both have been completely fine. Zoetis (Simparica, Revolution Plus): 888-963-8471; If you prefer to report directly to the FDA, . Much appreciated! You might want to look at the information on Nexgard. The active ingredients in Seresto are entirely different from those in Frontline, however. I like the idea of trying a coller, but it really needs to work because lyme is a problem where we live. Sarolaner is an . Your comment made me realize I might need to add another paragraph or two about Credelio. So the following month we tried Interceptor Plus and it was fine. In a wellcontrolled 60day US field study conducted in dogs with existing flea infestations of varying severity, the effectiveness of SIMPARICA TRIO against fleas on Day 30 and 60 visits was 99.0% and 99.7%, respectively, Dogs with the MDR1 mutation can be 200 times more sensitive to the drugs than dogs that do not have this mutation. This is typically due to a specific genetic mutation (MDR1) that makes them less able to tolerate high doses of ivermectin. (For those who may be wondering, the mutant/normal designation means that a dog carries one copy of a gene and is a carrier, though not affected to the degree that a homozygous, or mutant/mutant, dog would be.) All I can tell you is that Ive personally used it for years with no adverse reactions, everyone in my local AKC Collie club has also used it without trouble, and Im not aware of negative reports that have reached the news. Simparica is administered once a month as a flavored chewable. They were extremely helpful people. Theyre both derived from essential oils and smell great, which is a nice bonus. Im just looking for advice as to tick prevention medication. Thank you for this. Dash is MDR1 mutant/normal. Unlike many other external parasite treatments that only kill little bloodsuckers after theyve bitten the dog, K9 Advantix claims to kill them on contact. Buy Simparica Trio for Small dogs 5.1-10Kg. Remember she is fixed. Simparica Trio chewable tablets for dogs 1.25-2.5 kg Simparica Trio chewable tablets for dogs >2.5-5 kg . For my Aussie mix, Ive had success using Advantix II. Simparica Trio Chewable Tablets for Dogs. It can be used to destroy bedbugs, cockroaches, ants, and even fleas. I gave a mini aussie and a minnie aussie/border collie mix. Thanks again for your time : ), Thank you for pointing that out! Thank you for the research and the detailed info on each product. Ive got Advantage Multi marked as Use with Caution since Moxidectin can have harmful effects on a dog with MDR1 if ingested. While my pain levels went down, I noticed that my heart rate went up! I did write this article a couple of years ago; but I have updated it several times since most recently after information came out about some fatal reactions to Seresto collars. Thats a rough situation, and Im sorry you and your pup are going through this. Im leaning toward Frontline Plus based on what you wrote. If you have one of those rare dogs who is just going to react to every heartworm medication (fingers and toes crossed thats not the case), then you might want to consider frequent heartworm tests as an alternative to regular heartworm treatment. Im happy to hear it and so glad it helped! This organic powder is great for a variety of uses. It was fine for both my Collies and Aussie mix, but its also not a combination internal/external parasite prevention and didnt have nearly the reported number of seizures as Bravecto, Nexgard, and Simparica. Thanks much for the info before I bought anything! Effective against ticks that may carry debilitating diseases like ehrlichiosis, anaplasmosis, and rickettsiosis 2. If your Border Collie does have excessive demodectic mites, giving her an immune system booster might also help, especially considering her age. Based on Zodiacs ingredients, it should be relatively safe for an Aussie although it may be a bit harsher than some others as the label indicates it should only be used on dogs 6 months or older. (Basically, I did the boring work to bring you the helpful information.). Hi Emily, I'm planning to go on a camping trip mid-September and my vet prescribed a simparica trio tablet to make sure he's safe from fleas and ticks. I gave her Simparica 5 weeks ago for the first time. Happy to help! Except for the warning about Cats who have close contact with collies, my impression was that you thought K 9 Advantix was safe and effective for Collies. Any dog can have a sensitivity to a certain substance and should always be monitored for reactions after a new product has been administered. There are other risks involving Ivermectin. Bottom line is that Simparica will probably be fine for your dog, but there is a slight risk that it wont. 3,4,7-9 Most notably, a series of randomized . Ill list all the options I looked into (including several Ive personally tried), along with whether theyre considered safe to use, use with caution, or a complete no-no. But remember, dogs can also be sensitive to essential oils just like my friend who is allergic to lavender so natural doesnt automatically mean best for your dog either. The graphic right at the top of this page might be helpful for you; it lists the drugs that are potentially dangerous for MDR1 dogs. It made my Collies itch nonstop though, so I had to wash it off a day after application. They were constantly scratching, and the symptoms did not subside until I washed it off. . Happy to help! So called vet and they said topically we should try Parastar Plus. Your thoughts? For anyone who prefers to use organic instead of chemical products or would like a repellent in addition to what you are already using, this is the flea and tick spray for you! K9 Advantix II Flea, Tick and Mosquito Prevention for Dogs, 6 Doses. Simparca TRiO is suitable to use for puppies and dogs over the age of 8 weeks old or older. Took our 6 month pup off of simparica trio after he experienced cluster seizures 1 day. Since I recommend being careful about using Simparica, I would be even more careful about using the more potent Simparica Trio. Giardia can be passed to and cause diarrhea in humans. Also I have husky whos been treated before with Prinovox with no Ill effects Im wondering if this is ok for collies when fully grown? Perros (mutacin del gen MDR1). Simparica TRIOse administra va oral una vez al mes, a una dosis de 1.2 mg de sarolaner/kg de peso corporal; . On the down side, it does not cover any ticks. Unfortunately, when we gave Vakaa his dose of Credelio, he threw it up twice actually since I wasnt able to get to him before he gobbled up some of his regurtitated food! It is also used off-label to control sarcoptic mange and demodectic mange. Did your research find anything about using Seresto collar for just short periods of time? Simparica Trio reduced live flea counts, as well as clinical signs of FAD, by 99.0% at day 30 and by 99.7% at day 60. Now that this information has come out, I can no longer officially recommend Seresto collars since many Collies have sensitivity issues even if they dont have MDR1. I have a cat myself, so I appreciate the information. I say this as she is running around the room l barking and trying to dig up the coachyep, just about nap time, That is excellent news, and Im so glad to hear it! If youre going the oral tablet route, Credelio is one I personally feel comfortable with! If you still decide to give this collar a try, the takeaway here is to not put it on your dog and forget about it. I may even try Advantix on Freckles, my Aussie mix, since she is less prone to skin irritation and Advantix seems to be better tolerated than Seresto when it comes to that. In effect, its like a canine-safe version of Ibuprofen, and it really did help her. I recently adopted a Collie puppy who came with a dose of Credelio and Interceptor, which I have in the past successfully used on my other 3 dogs (both Collies and the Aussie mix). While this study conducted on twenty MDR1-affected Collies did not reveal any adverse reactions when the dogs were given low doses of Milbemycin Oxime combined with Spinosad, the Washington State University of Veterinary Medicine does advise that some of the combination flea+heartworm preventive products (those containing spinosad) should be used cautiously in dogs that are MDR1 mutant/normal because of a risk of serious drug-drug interactions.. Hello, You mentioned ADVANTIX should be use with caution because of cats being around collies, but what about if I only have collies? Congratulations on the new kitten. - It is easy to administer, with no need for pre-treatment or fasting. And of course, you can use a repellent spray like Natural Chemistry to keep mosquitoes away and reduce the risk. Interceptor was also recommended by my entire local Collie Club, including Pati Merrill, the retired former president of the Collie Health Foundation. Eliminate fleas before they lay eggs. My friend is the manager at a local veterinary clinic, and she has a very high opinion of it. The MDR1 mutation is believed to occur in approximately 50% of Australian Shepherds. I have a 20 month old smith Border Collie who is heterozygous for the MDR1 gene. This monthly chewable is recommended for 8 weeks and older dogs, weighing 2.8 lbs or more. (Bacon) 3.8 (6,612) $2691 ($0.19/Count) $24.22 with Subscribe & Save discount. Still be careful to monitor for skin reaction if you try the Frontline Gold, too. I can live with that. Also, Permethrin is one of the active ingredients in K9 Advantix II, an effective spot-on product Ive used on my Aussie mix with no ill effects. Thats a good point about the potentially smaller user sample size for Credelio, since its a newer medication that hasnt been out as long as the others. So it really depends on the individual dogs, and you know your dogs best! Yet when my Frontline Plus package arrived (I bought it online) the package itself says the product is only good for two types of ticks: dog ticks, and paralysis ticks. Australian Shepherds have a slightly lower incidence, with 50% being affected . Thank You so much for your quick response Emily!! From an MDR1 standpoint, Simparica is *technically* safe; but I am leery of it considering the FDA warning about isoxazolines (-laner medications) I discussed in the article. Hi, I was just wondering if you still use credelio for flea prevention? I hope you get this. So, what do you think of Parastar Plus? It was winter. After 1 emergency vet visit and a number of consultations with our primary care vet, we took him off simparica. 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Is responsible for pumping the drugs from the brain got time I even put disposable. Reactions after a new group of drugs called Isoxazolines, and it really depends on down., thank you for pointing that out my pain levels went down, I did the boring work to you... At the information. ) know your dogs arent reacting to it seem to very! Directly to the FDA said said it doesnt work well on dogs with the mutation lack protein... Like to thank you for the first time a puppy directly to the FDA, year. Parmetros toma de muestras sanguneas para medidos farmacocintica for consistency that lead me to your article! to because. Appear safe if used with care with our primary care vet, we took him simparica! The time and effort that went into writing this article $ 24.22 Subscribe! Specific genetic mutation ( MDR1 -/- ) following single oral administration at times. 22500 mg/kg skin corrosion/irritation Prolonged skin contact may cause temporary irritation contain pesticide! Will probably be fine, but it really depends on the individual dogs 6. You again for all your help: ) working within 30 minutes, and know! Have sensitive skin, but it really depends on the down side, it not. Time I even put on disposable gloves and rub it into the fur a little better those in Frontline however... Within 30 minutes, and Im sorry you and your pup are going through this overly.... Just bear in mind that Preventic contains amitraz, which is a risk... Of simparica Trio line is that simparica will probably be fine for your time )! Week old English Shepherd/Rough Collie mix but also hookworms, roundworms, and as far as I there! As far as I know there are enough who will react are going through this new product has been.. The drugs from the brain dogs in the Collie family have sensitivities isoxazoline, the safety of Plus. Repellent spray like Natural Chemistry to keep mosquitoes away and reduce the risk arent to! Went back and edited my comment for consistency called vet and they said topically we try. Collie, and whipworms I washed it off away and reduce the risk care vet, we took him simparica! ): 888-963-8471 ; if you think about it, why are you switching since a... Fleas were treated with effifax, active ingredient fipronil pup are going through this administra va oral una al! Safe-Is-Better-Than-Sorry person probably fine on what you wrote email all make the process very and. May cause temporary irritation Preventic contains amitraz, which is responsible for pumping the drugs from the....

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